Omeprazole Discovery, Mechanism and Use

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OMEPRAZOLE

Discovery;-

Omeprazole, was discovered in 1979. It is on the World Health Organization’s List of Essential medicines the most effective and safe medicines needed in a health and ist of the new class of drug.

Mechanism ;-

protan-pump inhibitor .

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Uses /Indication 

Omeprazole can be used in the treatment of gastroesophagael refluxdisese (GERD), peptic ulcer, and zollinger E2.

Pregnancy and breast-feeding;-

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Epidemiological data do not show an increased risk of major birth defects after maternal use of omeprazole during pregnancy .

Dose;-

Omeprazole is available as tablets and capsules (containing omeprazole or omeprazole magnesium) in strengths of 10, 20, 40, and in some markets 80 mg, BD two time in day AC and according to the condition of pateint treated with omeprazole. Treatment of H. pylori infection can be completed by taking a triple therapy combination of omeprazole, amoxicillin and clarithromycine for 7–14 days.

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